MicroSurfaces, Inc. enables the MEMS industry
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Advanced Surface Technologies for Protein Microarrays, Microfluidics & Biomedical Research


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  • High density PEG brush to prevent non-specific adsorption;
  • Robust bonds to the surface for long term coating stability;
  • Functional groups for the facile immobilization of proteins;
  • Chemical environment for long-term protein stability & optimal target-probe interaction.
  • Air-stable and fluidic supported lipid microarray for cell membrane microarrays.

Read the application notes: | PEG | Cu2+/PEG | NHS/PEG | Biotin/PEG | Maleimide/PEG | Membrane microarray |

chelated Cu2+ surface
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Zero background Cu2+ surface for the immobilization of poly-His taggerd proteins.
his-tagged protein microarray
A microarray of 6xHis tagged protein molecules spotted on the Cu2+/PEG surface. The protein was detected by immunostaining.

NHS surface
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Zero background NHS surface for the immobilization of proteins, peptides, antibody, & other molecules.
protein array on NHS surface
A microarray of fibrinogen fabricated on NHS/PEG/glass slides and detected by immunostaining.

biotinylated surface
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Zero background biotin/streptavidin surface for the immobilization of biotinylated molecules.
protein array on biotinlated surface
A microarray of biotin-conjugated BSA on the streptavidin/biotin/PEG surface. The immobilized BSA is detected by immonostaining.

maleimide surface
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 Zero background maleimide surface for the immobilization of molecules with -SH functional groups.
oligonucleotide array
Fluorescence image of dye-conjugated oligonucleotides with -SH termination covalently linked (hand spotted) on a Maleimide-PEG/glass slide.

air stable supported lipid bilayer'
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 glycan microarray
Multivalent binding curves of two E-coli strains on mannose density gradient microarrays (see inset). The upper shows two optical microscope images of E-coli cells adsorbed on SLB spots with 1% and 10% mannose, respectively.
Click here to read more about surface chemistry for protein immobilization.


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